When treating the signs and symptoms
of dry eye disease, TRYPTYR delivers
RAPID
NATURAL TEAR PRODUCTION
AS EARLY AS DAY 11
When treating the signs and symptoms of dry eye disease, TRYPTYR delivers
RAPID
NATURAL TEAR PRODUCTION
AS EARLY AS DAY 11
NEW TRYPTYR: a first-in-class neuromodulator eye drop that rapidly increases natural tear production as early as Day 11-5
NEW TRYPTYR: a first-in-class neuromodulator eye drop that rapidly increases natural tear production as early as Day 11-5
Simple dosing with TRYPTYR1

TRYPTYR works differently1-5
See how TRYPTYR rapidly increases tear production by stimulating corneal sensory nerves1
TRYPTYR works differently1-5
See how TRYPTYR rapidly increases tear production by stimulating corneal sensory nerves1
Help your patients benefit from rapid natural tear production
REFERENCES
- TRYPTYR. Prescribing Information. Alcon, Inc., 2025.
- Restasis. Prescribing Information. AbbVie; 2024.
- Xiidra. Prescribing Information. Bausch & Lomb; 2023.
- Tyrvaya. Prescribing Information. Oyster Point Pharma, Inc., 2024.
Miebo. Prescribing Information. Bausch & Lomb; 2023.
IMPORTANT SAFETY INFORMATION
Warnings and Precautions
Potential for Eye Injury and Contamination: To avoid the potential for eye injury and contamination, advise patients not to touch the vial tip to the eye or other surfaces.
INDICATIONS AND USAGE
TRYPTYR (acoltremon ophthalmic solution) 0.003% is indicated for the treatment of the signs and symptoms of dry eye disease (DED).
Use with Contact Lenses: TRYPTYR should not be administered while wearing contact lenses. If contact lenses are worn, they should be removed prior to administration of the solution. Lenses may be reinserted 15 minutes following administration.
Adverse Reactions
In clinical trials, the most common adverse reaction was instillation site pain (50%).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please click here for the TRYPTYR Full Prescribing Information.